Insulin secretion and food intake

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Insulin secretion and food intake.

Metabolic stimulation of insulin release Various metabolites are known to stimulate insulin release. As reviewed in detail elsewhere (Hager, Pipeleers, Herchuelz & Malaisse, 1972), glucose and mannose are the only sugars which have consistently been found to exert a significant insulinotropic action. They are also the only sugars to stimulate insulin biosynthesis in the /3 cell. The relationshi...

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Brain Insulin Receptors: Effects on Food Intake, Learning and Memory

Insulin and insulin receptors have been demonstrated in mammalian brain but until recently their function remained illusive. Insulin receptors are predominantly expressed in the olfactory bulbs, hypothalamus, and hippocampus. Recent studies have shown that insulin acts in the control of diverse brain functions such as neuronal survival, regulation of energy homeostasis, reproduction, food intak...

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Insulin controls food intake and energy balance via NPY neurons

OBJECTIVES Insulin signaling in the brain has been implicated in the control of satiety, glucose homeostasis and energy balance. However, insulin signaling is dispensable in energy homeostasis controlling AgRP or POMC neurons and it is unclear which other neurons regulate these effects. Here we describe an ancient insulin/NPY neuronal network that governs energy homeostasis across phyla. METH...

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This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...

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ژورنال

عنوان ژورنال: Proceedings of the Nutrition Society

سال: 1972

ISSN: 0029-6651,1475-2719

DOI: 10.1079/pns19720039